Peripheral Effects of Rimonabant on Upper Gastrointestinal Motility
نویسندگان
چکیده
منابع مشابه
Peripheral Effects of Rimonabant on Upper Gastrointestinal Motility
Drugs that interfere with cannabinoid CB1 receptor transmission suppress a number of food-related behaviours and these compounds are currently being assessed for their potential utility as appetite suppressants. Rimonabant (SR 141716A) is a cannabinoid receptor 1 (CB1) antagonist-inverse agonist which was developed for obesity treatment [1]. Clinical trials showed that rimonabant caused cumulat...
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BACKGROUND Obesity and overweight affect more than half of the US population and are associated with a number of diseases. Rimonabant, a cannabinoid receptor 1 blocker in the endocannabinoid (EC) system, was indicated in Europe for the treatment of obesity and overweight patients with associated risk factors but withdrawn on Jan, 2009 because of side effects. Many studies have reported the effe...
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ژورنال
عنوان ژورنال: Internal Medicine: Open Access
سال: 2012
ISSN: 2165-8048
DOI: 10.4172/2165-8048.1000116